A new framework for computational protein design through cost function network optimization
نویسندگان
چکیده
منابع مشابه
Computational Protein Design as a Cost Function Network Optimization Problem
Proteins are chains of simple molecules called amino acids. The three-dimensional shape of a protein and its amino acid composition define its biological function. Over millions of years, living organisms have evolved and produced a large catalog of proteins. By exploring the space of possible amino-acid sequences, protein engineering aims at similarly designing tailored proteins with specific ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt374